How do antimetabolites work?

How do antimetabolites work?

Antimetabolites are called a “cytotoxic” type of drug because they kill cells. They work by mimicking the molecules that a cell needs to grow. Cells are tricked into taking in the drugs and then using the antimetabolites instead of their normal building blocks of genetic material: RNA and DNA.

How does a radiotherapy machine work?

Most radiation therapy machines use photon beams. Photons are also used in x-rays, but x-rays use lower doses. Photon beams can reach tumors deep in the body. As they travel through the body, photon beams scatter little bits of radiation along their path.

How do chemotherapeutic drugs work?

Chemotherapy is the use of drugs to destroy cancer cells. It usually works by keeping the cancer cells from growing, dividing, and making more cells. Because cancer cells usually grow and divide faster than normal cells, chemotherapy has more of an effect on cancer cells.

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Why would a doctor order a CT scan after a colonoscopy?

The major reason for performing CT colonography is to screen for polyps or cancers in the large intestine. Polyps are growths that arise from the inner lining of the intestine. A very small number of polyps may grow and turn into cancers.

Which one of the following is antimetabolite drug?

List of Antimetabolites:

Drug Name Avg. Rating Reviews
Otrexup (Pro) Generic name: methotrexate 9.5 2 reviews
Rheumatrex Dose Pack (Pro) Generic name: methotrexate 2.0 1 review
Purinethol (Pro) Generic name: mercaptopurine 7.6 1 review
Leustatin (Pro) Generic name: cladribine 10 1 review

What processes could antimetabolites interfere with?

Antimetabolites interfere with the synthesis of DNA, RNA, and ultimately proteins. They exert their effects largely in the synthetic (S) phase of the cell cycle. Some antimetabolites are structural analogs of normal metabolites essential for cell growth and replication.

Is radiotherapy worse than chemotherapy?

When radiotherapy is used try to cure the cancer completely (curative radiotherapy) make other treatments more effective – for example, it can be combined with chemotherapy or used before surgery (neo-adjuvant radiotherapy) reduce the risk of the cancer coming back after surgery (adjuvant radiotherapy)

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How does chemotherapy make you feel?

Common side effects Chemotherapy can cause fatigue, loss of appetite, nausea, bowel issues such as constipation or diarrhoea, hair loss, mouth sores, skin and nail problems. You may have trouble concentrating or remembering things. There can also be nerve and muscle effects and hearing changes.

Why do you experience unpleasant side effects from chemotherapy?

Why does chemo cause side effects? Cancer cells tend to grow fast, and chemo drugs kill fast-growing cells. But because these drugs travel throughout the body, they can affect normal, healthy cells that are fast-growing, too. Damage to healthy cells causes side effects.

Can I have an MRI instead of a colonoscopy?

NEW YORK (Reuters Health) – The use of magnetic resonance imaging, or MRI, may offer a more tolerable alternative to conventional colonoscopy in screening for colon cancer, new research suggests. With MRI colonography, images are taken of the colon that resemble those seen with colonoscopy.

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