Which antimicrobial drug is suitable for treatment of both TB and leprosy?

Which antimicrobial drug is suitable for treatment of both TB and leprosy?

– Antibiotic rifampicin is used to treat bacterial infections. It stops germs from spreading throughout the body. It is employed in the treatment and prevention of tuberculosis (TB). It can also be used to get rid of germs in the nose and throat that can lead to meningitis, leprosy, and other diseases.

What antimicrobials are used to treat TB?

Of the approved drugs, the first-line anti-TB agents that form the core of treatment regimens are:

  • isoniazid (INH)
  • rifampin (RIF)
  • ethambutol (EMB)
  • pyrazinamide (PZA)

Which of the following is used in the treatment of TB leprosy?

Minocycline and dapsone therapy was initiated during the workup for TB and changed to rifampin (Rif), isoniazid, pyrazinamide, and ethambutol, with the addition of dapsone once coinfection was confirmed.

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Which was the first antimicrobial agent used to treat tuberculosis?

The first line of inquiry was the development of antibiotics from the first antibiotic (penicillin) to the first antibiotic successfully used to treat tuberculosis (streptomycin) (7, 8).

Which class of antibiotic is streptomycin?

Streptomycin belongs to a class of drugs known as aminoglycoside antibiotics. It works by killing the organisms that cause the infection. This drug may also be used to treat other serious infections (e.g., Mycobacterium avium complex-MAC, tularemia, endocarditis, plague) along with other medications.

Is dapsone used to treat tuberculosis?

Dapsone exhibits activity against Mycobacterium tuberculosis and Mycobacterium avium complex (MAC) in vitro. We retrospectively examined the incidence of mycobacterial diseases within a randomized prospective trial of prophylaxis for Pneumocystis carinii pneumonia and toxoplasmosis.

What is ATT treatment?

Efficacy and safety of modified anti-tubercular treatment(ATT) regimens in treatment of tuberculosis(TB) in patients with underlying chronic liver disease(CLD)

What is the best treatment for leprosy?

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In general, two antibiotics (dapsone and rifampicin) treat paucibacillary leprosy, while multibacillary leprosy is treated with the same two plus a third antibiotic, clofazimine. Usually, medical professionals administer the antibiotics for at least six to 12 months or more to cure the disease.

WHO recommended treatment for leprosy?

What is the WHO recommended multidrug regimen for treatment of leprosy?

Age Group Drug Dosage and Frequency
Adult Clofazimine 300 mg once a month and 50 mg daily
Dapsone 100 mg daily
Children (10-14 years) Rifampicin 450 mg once a month
Clofazimine 150 mg once a month, 50 mg on alternate days

What is penicillin drug?

What is penicillin? Penicillin V is an antibiotic in the penicillin group of drugs. It fights bacteria in your body. Penicillin V is used to treat many different types of infections caused by bacteria, such as ear infections,. Penicillin V may also be used for other purposes not listed in this medication guide.

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Is rifampin an antibacterial drug?

This medication is a rifamycin antibiotic used to prevent and treat tuberculosis and other infections. This antibiotic treats only bacterial infections. It will not work for viral infections (such as common cold, flu).