What does Hep C genotype 1a mean?

What does Hep C genotype 1a mean?

Background. Hepatitis C virus (HCV) genotype 1 is the most prevalent worldwide. Subtype 1a, compared with 1b, shows lower response rates and higher propensity to select for drug resistance to NS3 and selected NS5A and nonnucleoside NS5B inhibitors. Two distinct clades of subtype 1a have been described.

What is the most commonly recommended treatment protocol for HCV?

Hepatitis C is treated using direct-acting antiviral (DAA) tablets. DAA tablets are the safest and most effective medicines for treating hepatitis C. They’re highly effective at clearing the infection in more than 90\% of people. The tablets are taken for 8 to 12 weeks.

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What type of precautions should be used for patients with HCV?

Universal precautions for hepatitis C use appropriate protective measures when there is a chance of exposure to blood or bodily fluids, such as wearing gloves, gowns, masks, and protective eyewear. remove and safely dispose of personal protective equipment (PPE), needles, and other devices after procedures.

What is the most common Hep C genotype?

HCV subtypes 1a and 1b are the most common genotypes in the United States (Fig. ​ 3) (145). These subtypes also are predominant in Europe (35, 82, 91).

What is hepatitis genotype?

A genotype is a way to put the hepatitis C virus (HCV) into categories based on similar genes. It’s important to know and understand HCV genotypes because different genotypes respond differently to medicines that treat and cure HCV. HCV has six genotypes, labeled 1 through 6.

How is HCV genotype determined?

The genotype of HCV for diagnosis is mostly determined by sequencing of genomic nucleotide sequence or by kit-based assays which employ complementary probes to report genotype present in a specimen.

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How do you treat Hep C positive?

Hepatitis C infection is treated with antiviral medications intended to clear the virus from your body. The goal of treatment is to have no hepatitis C virus detected in your body at least 12 weeks after you complete treatment.

Is it safe to be around someone with hep C?

If you live with someone who has hepatitis C, there’s no reason to avoid close personal contact. Feel free to touch, kiss, and cuddle. The most important thing you can do to prevent getting the virus is to avoid contact with the infected person’s blood. Blood can be infectious even when it’s dry.

What is hep C positive?

Negative – this means you were infected with hepatitis C virus, but the virus is no longer in your body because you were cured or cleared the virus naturally. Positive – this means you currently have the virus in your blood and are infectious, meaning you can spread the virus to others.

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Why is HCV genotyping done?

Can HCV genotype change?

Six major genotypes of the hepatitis C virus (HCV) have been described; it is assumed to be uncommon for genotypes to change in chronically infected individuals.