Table of Contents
- 1 What are the functional elements of a genome?
- 2 What did the Encode project find?
- 3 How do you determine the function of a gene?
- 4 What is ENCODE genome?
- 5 Which among the following factors are commonly used for sequencing human genome?
- 6 What is the goal of a genome sequencing project quizlet?
- 7 Can functional genomics be applied to skeletal and mineral cells?
- 8 What determines the meaning of the information encoded in the genome?
What are the functional elements of a genome?
Decades of detailed studies of gene regulation and RNA metabolism have defined major classes of functional noncoding elements, including promoters, enhancers, silencers, insulators, and noncoding RNA genes such as microRNAs, piRNAs, structural RNAs, and regulatory RNAs (50⇓⇓–53).
What did the Encode project find?
The ENCODE Project has given researchers insight into how the human genome functions. As researchers learn more about the regulation of gene activity and how genes are expressed, the scientific community will be able to better understand how the entire genome can affect human health.
What are 3 ethical issues with the Human Genome Project?
The original issues identified in the ELSI program announcement were: questions of fairness in the use of genetic information; the impact of genetic information on individuals; privacy and confidentiality of genetic information; the impact of the HGP on genetic counseling; the impact of genetic information on …
What do you mean by functional genomics?
Functional genomics is the study of how genes and intergenic regions of the genome contribute to different biological processes. Functional genomics focuses on the dynamic expression of gene products in a specific context, for example, at a specific developmental stage or during a disease.
How do you determine the function of a gene?
Clues to gene function can often be obtained by examining when and where a gene is expressed in the cell or in the whole organism. Determining the pattern and timing of gene expression can be accomplished by replacing the coding portion of the gene under study with a reporter gene.
What is ENCODE genome?
ENCODE is a public research consortium aimed at identifying all functional elements in the human and mouse genomes.
Which of the following is a major finding from the ENCODE project?
The ENCODE consortium’s major findings include the discovery that the majority of DNA in the human genome is transcribed into functional molecules, called RNA, and that these transcripts extensively overlap one another.
How can genomic research improve detection and diagnosis of human diseases?
Genomic medicine has the potential to make genetic diagnosis of disease a more efficient and cost-effective process, by reducing genetic testing to a single analysis, which then informs individuals throughout life.
Which among the following factors are commonly used for sequencing human genome?
Commonly used vector for human genome sequencing are BAC and YAC. BAC is a DNA construct, based on a functional fertility plasmid (F-plasmid) used for genetically engineered chromosomes derived from the DNA of the yeast, Saccharomyces cerevisiae which is then ligated into a bacterial plasma.
What is the goal of a genome sequencing project quizlet?
research endeavors that have the ultimate goal of determining the sequence of DNA bases of the entire genome of a given species.
What is functional genomics in microbiology?
Functional Genomics. Functional genomics is a branch that integrates molecular biology and cell biology studies, and deals with the whole structure, function and regulation of a gene in contrast to the gene-by-gene approach of classical molecular biology technique.
Does functional genomics provide adequate data to evaluate behavioral genetic toolkits?
Thus functional genomics studies at the whole-genome scale may provide adequate data to evaluate behavioral genetic toolkits from multiple viewpoints. Functional genomics advances have led to the development of high-throughput techniques that enable expression profiling within discrete brain regions and specific cell types.
Can functional genomics be applied to skeletal and mineral cells?
The methods in functional genomics described earlier can be applied to other cells and tissues that play a role in skeletal and mineral homeostasis. For example, there is a lack of knowledge of the specific transcriptional program that governs parathyroid cells.
What determines the meaning of the information encoded in the genome?
The order of the As, Ts, Cs and Gs determines the meaning of the information encoded in that part of the DNA molecule just as the order of letters determines the meaning of a word. What is a genome? An organism’s complete set of DNA is called its genome.