Table of Contents
How long can you live with Evans syndrome?
The median survival with Evans syndrome was 7.2 years (primary Evans syndrome: 10.9 years; secondary Evans syndrome: 1.7 years). Secondary Evans syndrome was associated with higher mortality rates than any of the other cohorts, with a 5-year survival of 38\%.
How do you test for Evans syndrome?
Doctors diagnose Evans syndrome with a variety of blood tests, including:
- complete blood count.
- Coombs test: a blood test that identifies the cause of anemia.
- reticulocyte count: a blood test that measures how fast new red blood cells called reticulocytes are made by bone marrow and released into the blood.
Is Evans syndrome life threatening?
Evans syndrome can potentially cause severe, life-threatening complications. Evans syndrome may occur by itself as a primary (idiopathic) disorder or in association with other autoimmune disorders or lymphoproliferative disorders as a secondary disorder.
Can Evans syndrome go away?
While there is no one cure for Evans syndrome, there are many methods that used to manage symptoms. For some individuals, treatment can lead to long periods of remission in which the signs and symptoms of Evans syndrome are more mild or disappear.
Who does Evans syndrome affect?
A Danish study of adults with Evans syndrome found that it may affect up to 21.3 of every million people. According to the NORD, the incidence and prevalence of Evans syndrome are unknown. The organization describe this condition as rare.
How rare is Evans syndrome?
Evans syndrome is considered a very rare autoimmune disease. Only one study has estimated incidence and prevalence adults. In Denmark in 2016 the annual incidence was 1.8 per 1,000,000 person years, and the prevalence was 21.3 per 1,000,000 living persons.
What is secondary Evans syndrome?
Evans syndrome is an autoimmune condition that presents with two or more cytopenias, which commonly includes autoimmune hemolytic anemia (AIHA) and immune thrombocytopenia (ITP), with or without immune neutropenia. It can be primary (or idiopathic) or secondary (i.e., associated with an underlying disorder).
What autoimmune disease causes low iron?
Anemia is a lower-than-normal number of red blood cells in the blood. ACD is a common cause of anemia. Some conditions that can lead to ACD include: Autoimmune disorders, such as Crohn disease, systemic lupus erythematosus, rheumatoid arthritis, and ulcerative colitis.
What is the cure for Evans Syndrome?
There is no cure for Evans syndrome, so treatment focuses on relieving symptoms and increasing blood cell counts. Treatment for Evans syndrome varies from person to person.
What Autoimmune disease causes low iron?
How do you treat Evans syndrome?
Corticosteroids and IVIG are the first-line treatment options for Evans syndrome. Rituximab is the preferred second-line treatment. Other treatment options include splenectomy, danazol, and immunosuppressants.