Which drug is used as calcium channel blockers in hypertension?
Examples of calcium channel blockers include: Amlodipine (Norvasc) Diltiazem (Cardizem, Tiazac, others) Felodipine.
What is the first drug of choice for hypertension 2020?
The strongest body of evidence indicates that for most patients with hypertension, thiazide diuretics are the best proven first-line treatment in reducing morbidity and mortality.
What is the drug of choice for hypertension?
Generally, ACE inhibitors should remain the initial treatment of choice for hypertension. Angiotensin II receptor antagonists or angiotensin receptor blockers (ARBs) are used for patients who are unable to tolerate ACE inhibitors.
Which is better amlodipine or felodipine?
Amlodipine seems to be more effective than felodipine when the drugs are compared in the same dose, with regard to the effect on clinic BP 24 h after dosing and to ambulatory BP during the night. The longer elimination half-life of amlodipine as compared to felodipine is the probable reason for this finding.
What is dihydropyridine used for?
Because of their selective effect on arterial blood vessels, dihydropyridines are mainly used to decrease vascular resistance and blood pressure, and therefore are used to treat hypertension. Other uses of dihydropyridines include preventive treatment of stable angina, Raynaud’s syndrome, and cerebral vasospasm.
Is Amlodipine a dihydropyridine calcium channel blocker?
Dihydropyridines — The dihydropyridines, including nifedipine, isradipine, felodipine, nicardipine, nisoldipine, lacidipine, amlodipine, and levamlodipine are potent vasodilators that have little or no negative effect clinically upon cardiac contractility or conduction.
Which calcium channel blocker causes the least edema?
Diltiazem, a non-DHP agent, seems to be associated with the lowest incidence of ankle oedema.
What is the difference between dihydropyridine and non dihydropyridine calcium channel blockers?
While all approved calcium channel blockers inhibit the L-type calcium channel on cells, they are divided into two major categories based upon their predominant physiologic effects: the dihydropyridines, which are predominantly vasodilators and generally have limited chronotropic and inotropic effects, and the non- …