Table of Contents
What is normal range of HCV RNA?
This assay has a result range of 15 to 100,000,000 IU/mL (1.18 log to 8.00 log IU/mL) for quantification of hepatitis C virus (HCV) RNA in serum. An “Undetected” result indicates that the HCV is absent in the patient’s serum specimen.
What is a high level of HCV RNA?
The quantitative HCV RNA test is checked before a patient starts treatment. For each patient, the result can be described as either a “high” viral load, which is usually >800,000 IU/L, or a “low” viral load, which is usually <800,000 IU/L. It’s not uncommon to have a viral load in the millions.
What is a good HCV ratio?
Reactive results with S/Co ratios of 8.0 or greater are highly predictive (95\% or greater probability) of the true anti-HCV status, but additional testing is needed to differentiate between past (resolved) and chronic hepatitis C.
How do you read HCV test results?
The first test is the hep C RNA qualitative test, also known as the PCR test. A positive result means that a person has the hepatitis C virus. A negative result means that the body has cleared the virus without treatment. The second test is the hep C RNA quantitative test.
How accurate is HCV RNA test?
RNA: This test measures the number of viral RNA (genetic material from the hepatitis virus) particles in your blood, also called the “viral load.” The RNA test is almost 100\% accurate and can detect an infection within a couple of weeks after exposure.
What is considered a high HCV viral load?
High viral load: This is when your count is more than 800,000 IU/mL. If your viral count is high at the start, it can be hard or impossible for your treatment to completely get rid of the virus. Some researchers consider high levels anything above 400,000 IU/mL. Low viral load: This is a count below 800,000 IU/mL.
What is HCV 10?
Abstract. The serum concentration of hepatitis C virus (HCV) RNA is usually stable (4 to 8 log(10) IU/ml) in untreated patients with chronic hepatitis C.
What is HCV S CO ratio?
Conclusion: S/CO ratio is a useful indicator in predicting HCV viremia among anti-HCV-reactive hemodialysis patients. Patients with an S/CO ratio >65 can be regarded as those with active HCV infection. Alternatively, patients with reactive anti-HCV but with an S/CO ratio <65 should receive further RT-PCR test.
What is a signal to cutoff ratio?
Results are calculated as normalized signal-to-cutoff (S/Co) ratios obtained by measuring the signal strength of sample and the signal strength of an internal cutoff. Samples with an S/Co ratio of ≥1.0 are defined by the manufacturer as positive.
What is the normal range of hepatitis?
Any value between 1 and 5 s/c is indeterminate and should be repeated. For hepatitis B surface antibody (anti-HBs), a level less than 5 mIU is considered negative, while a level more than 12 mIU is considered protective. Any value between 5 and 12 mIU is indeterminate and should be repeated.
What is HCV RNA NAA qualitative?
The Hepatitis C (HCV), RNA Qualitative NAA test is used to detect and confirm Hepatitis C virus infection in patients. Hepatitis C is a bloodborne liver disease, where exposure to the blood of an infected person may result in infection. Abnormal results may require further evaluation by your physician.
What is one level of detectable HCV RNA?
HCV RNA tests must have an LLOQ of 25 IU/mL or lower when used to assess treatment response with DAAs. LLOQ = the lowest HCV RNA level that is within the linear and analytically acceptable range of the assay. LLOD = the lowest level of HCV RNA that is detected ≥95\% of the time. Interpreting HCV RNA Test Results
What does negative for HCV RNA mean?
Negative for HCV RNA means there were no Hep-C viruses detected in your blood. This means you don’t have an active Hep-C infection. This is great news and suggests that you were previously exposed to the virus but never developed an infection. Re: What does Negative for HCV RNA mean? Some people’s own immune system is able to cure itself.
Who needs to be tested for hepatitis C?
The U.S. Preventive Services Task Force recommends that all adults ages 18 to 79 years be screened for hepatitis C, even those without symptoms or known liver disease. Screening for HCV is especially important if you’re at high risk of exposure, including: Anyone who has abnormal liver function test results with no identified cause
What is normal range of HBV DNA?
Results: The median level of HBV DNA among inactive carriers was 3.70 log (10) copies/mL (range, undetectable to 5.98 log (10) copies/mL). Ninety (36\%) had levels of 10 (4) copies/mL or greater.