Table of Contents
What is the chemical make up of GHB?
C4H8O3
GHB has the molecular formula C4H8O3 and the molecular weight 104.10 g/mol. It is a powdered substance and is generally dissolved in a liquid. In liquid form, GHB is clear and colorless, and slightly salty in taste.
Does GHB have long-term effects?
There is limited information about the impact of long-term GHB use on people’s health. While the main long-term risk is dependence, other reported long-term effects include: severe memory problems. heart disease.
Is GHB bad for your brain?
Summary: Scientists have discovered that regular use of the party drug GHB, and especially unconsciousness following GHB use, is associated with brain changes including negative effects on long-term memory, working memory, IQ, and higher levels of stress and anxiety.
What is the difference between GHB and Xyrem?
The prescription drug Xyrem is the sodium salt of gamma-hydroxybutyrate (GHB). GHB has not been approved for any medical use and has the potential for abuse, such as in cases of sexual assault. GHB is a Schedule I controlled substance under the Controlled Substances Act.
What is the pharmaceutical value of GHB?
The drug’s street value is about $200 an ounce. The Drug Enforcement Administration says that GHB has been linked to 66 deaths and some 5,700 overdoses, but, as disturbing as those numbers are, they may only be the beginning of the outbreak.
Is GABA A GHB?
Gamma-hydroxybutyric acid (GHB) is a psychoactive drug and a putative neurotransmitter, derived from gamma-aminobutyric acid (GABA). This action of GHB occurs in the presence of GABA(B) blockade and is antagonized by NCS-382, a specific GHB receptor antagonist, suggesting that it is mediated by GHB receptors.
What receptors does GHB use?
GHB acts as an agonist at a specific inhibitory GHB receptor in the cortex and hippocampus of the brain, and also as an agonist at GABAB receptors, which mediate its sedative effects. GHB receptor activation stimulates dopamine release.
What is GHB, and why is it so dangerous?
What is GHB and why is it so dangerous? GHB is a naturally-occurring neurotransmitter, as well as an illegal drug. GHB molecules exist in all of us and they are involved in the everyday functioning of the brain.
What are the effects of using GHB?
Euphoria, increased sex drive, and tranquility are reported positive effects of GHB abuse. Negative effects may include sweating, loss of consciousness, nausea, hallucinations, amnesia, and coma, among other side effects.
How to make gamma butyrolactone?
γ-Butyrolactone is produced industrially by dehydrogenation of 1,4-butanediol at a temperature of 180–300 °C and atmospheric pressure in the presence of a copper catalyst. The yield of this process is approximately 95\%. The purification takes place with a liquid-gas-phase extraction.
What is GHB prescribed for?
GHB is the active ingredient in the prescription medication sodium oxybate ( Xyrem ). Sodium oxybate is approved by the U.S. Food and Drug Administration (FDA) for the treatment of cataplexy associated with narcolepsy and excessive daytime sleepiness (EDS) associated with narcolepsy.