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What happens in idiopathic thrombocytopenic purpura?
Idiopathic thrombocytopenic purpura is a blood disorder characterized by an abnormal decrease in the number of platelets in the blood. A decrease in platelets can result in easy bruising, bleeding gums, and internal bleeding. ITP may be acute and resolve in less than 6 months, or chronic and last longer than 6 months.
How serious is thrombocytopenic purpura?
Thrombotic thrombocytopenic purpura (TTP) can be fatal or cause lasting damage, such as brain damage or a stroke, if it’s not treated right away. In most cases, TTP occurs suddenly and lasts for days or weeks, but it can go on for months.
Is idiopathic thrombocytopenic purpura hereditary?
Chronic ITP typically affects adults. Most adults with ITP are young women, but it can occur in anyone. ITP does not seem to be hereditary (run in families). ITP is not contagious (you can’t “catch it” from someone else).
What is the fastest way to get rid of purpura?
How is purpura treated?
- Corticosteroids. Your doctor may start you on a corticosteroid medication, which can help increase your platelet count by decreasing the activity of your immune system.
- Intravenous immunoglobulin.
- Other drug therapies.
- Splenectomy.
How do you identify purpura?
Small purple spots on the skin, typically 4–10 millimeters (mm) in diameter, characterize purpura. Some people develop areas of spots 2mm or even smaller. These are called petechiae. Some people develop larger patches of 1 centimeter or greater.
What medications cause purpura?
Other drugs associated with drug purpura include the following:
- Antibiotics (eg, cephalosporins, rifampicin)
- Gold salts.
- Analgesics.
- Neuroleptics.
- Diuretics.
- Antihypertensives.
What drugs can cause purpura?
Strong steroids. Long-term use of strong steroids can cause widespread purpura and bruising, normally on extensor surfaces of the hands, arms and thighs. It is caused by atrophy of the collagen fibres supporting blood vessels in the skin.
What causes TTP blood disorder?
Thrombotic thrombocytopenic purpura. Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that causes blood clots to form in small blood vessels. This leads to a low platelet count (thrombocytopenia). This disease may be caused by problems with an enzyme (a type of protein) that is involved in blood clotting.
What is idiopathic RBD?
REM sleep behavior disorder (RBD) is a parasomnia characterized by dream-enacting behavior and loss of muscle atonia during REM sleep. Idiopathic RBD occurs in the absence of any neurological disease or other possible cause, is male-predominant and its clinical course is generally chronic progressive.