Has anyone died taking too much Benadryl?

Has anyone died taking too much Benadryl?

Overdosage of diphenhydramine may result in the development of anticholinergic symptoms, seizures, and coma. A fatal outcome following a diphenhydramine overdose does not commonly occur. This report describes the largest documented overdosage of diphenhydramine (7.5 g) which resulted in the death of a 14-year-old girl.

Can you overdose from Benadryl pills?

Overdose warning Although online challenges may encourage it, it is not safe to take more than the recommended dosage of Benadryl. Doing so can lead to overdose and severe symptoms, including abnormal heart rhythms, hallucinations, seizures, and even death in rare cases.

What is the LD 50 of Benadryl?

LD50/LC50: RTECS: CAS# 147-24-0: Oral, mouse: LD50 = 164 mg/kg; Oral, rat: LD50 = 500 mg/kg; .

What is delirium and psychosis?

Delirium may be a common cause of psychotic symptoms such as hallucinations, bizarre delusions and thought-disorder, even in conditions such as schizophrenia, mania and depression, where delirium has traditionally been excluded by definition.

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What is a drug-induced psychosis?

Psychosis is a mental health problem that temporarily causes someone to interpret the world differently from those around them. Drug-induced psychosis, also known as ‘stimulant psychosis’, happens when you experience episodes of psychosis such as delusions or hallucinations as a direct result of substance abuse.

Can Benadryl damage your brain?

Potential harm to the brain: Long-term anticholinergic use has been associated with increased dementia risk; diphenhydramine can impair many cognitive functions including memory.

Does Benadryl cause delirium?

An observational study of older hospitalized patients reported that diphenhydramine treatment significantly increased risk for delirium symptoms, including inattention, disorganized speech, and altered consciousness [9]. Older adults with kidney or liver impairment are especially prone to these adverse effects [1].