Why does hypertrophic cardiomyopathy cause sudden death?

Why does hypertrophic cardiomyopathy cause sudden death?

When patients complain of symptoms, these include: dyspnea, dizziness, syncope and angina. HCM can lead to sudden cardiac death (SCD), mainly due to ventricular tachyarrhythmia or ventricular tachycardia. High-risk patients benefit from implantable cardioverter-defibrillators.

Can you have cardiomyopathy without symptoms?

There might be no signs or symptoms in the early stages of cardiomyopathy. But as the condition advances, signs and symptoms usually appear, including: Breathlessness with activity or even at rest.

Can you die from hypertrophic cardiomyopathy?

Rarely, hypertrophic cardiomyopathy can cause heart-related sudden death in people of all ages. Because many people with hypertrophic cardiomyopathy don’t realize they have it, sudden cardiac death may be the first sign of a problem.

How many deaths occur each year from HCM?

Conclusions: In young people without symptoms hypertrophic cardiomyopathy is fairly common (1 in 500) but it rarely causes death; the case-fatality rate is about 6 per 10,000 per year.

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What is end stage hypertrophic cardiomyopathy?

One of the most serious manifestations of HCM, apart from sudden death, is progressive systolic heart failure (HF) often coupled with ventricular dilatation, which for the lack of a better name, is referred to as end-stage HCM.

Can sudden cardiac death be prevented?

Every year, more than 7,000 children and teens die in the U.S. from sudden cardiac arrest (SCA). Many of these deaths can be prevented if children and parents recognize the early warning signs of SCA and seek medical attention before a crisis occurs.

Can you die of hypertrophic cardiomyopathy?

1-year survival rate for Hypertrophic cardiomyopathy: About 2 to 3 percent die each year because the heart suddenly stops beating. 10-year survival rate for Hypertrophic cardiomyopathy: Over 10 years, the risk of sudden death can be 20 percent or more.

What are the predictors of sudden cardiac death?

While low blood pressure and a high resting heart rate are strong initial predictors of sudden cardiac death, over time, heart failure and an earlier heart attack can be even more robust predictors.

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Who is at risk for hypertrophic cardiomyopathy?

Hypertrophic cardiomyopathy (HCM) can affect people of any age. It affects men and women equally. It is a common cause of sudden cardiac arrest in young people, including young athletes. Hypertrophic cardiomyopathy occurs if heart muscle cells enlarge and cause the walls of the ventricles (usually the left ventricle) to thicken.

Why is hypertrophic cardiomyopathy dangerous?

Hypertrophic obstructive cardiomyopathy results in abnormal thickening of the myocardium, most commonly in the interventricular septum, with pathologic “myocardial disarray” upon microscopic inspection. HOCM can lead to clinical heart failure, life-threatening arrhythmias, mitral regurgitation and sudden cardiac death.