Table of Contents
Which statement best describes a protein domain?
What of the following best describes a protein domain? A relatively large pattern of three-dimensional structure that is recognized across many proteins.
How many domains does a protein have?
For example, Src (pronounced ‘sark’), a kinase that has a key role in intracellular signalling, has four domains: the catalytic activity of the protein resides in two domains (kinase domains) and the other two domains are important for the regulation of this activity (regulatory domains).
What is a domain in a protein?
Domains are distinct functional and/or structural units in a protein. Usually they are responsible for a particular function or interaction, contributing to the overall role of a protein. Domains may exist in a variety of biological contexts, where similar domains can be found in proteins with different functions.
What is domain in math definition?
The domain of a function is the set of all possible inputs for the function. For example, the domain of f(x)=x² is all real numbers, and the domain of g(x)=1/x is all real numbers except for x=0. We can also define special functions whose domains are more limited.
How do you identify protein function?
Because proteins with similar structures often have similar functions, the biochemical activity of a protein can sometimes be predicted by searching for known proteins that are similar in their amino acid sequences. Further clues to the function of a protein can be derived from examining its subcellular distribution.
Which term best describes proteins?
A protein is best described as a polypeptide as they consist of a large number of α-amino acids that are linked together into a long chain by means of peptide linkages.
What is the best description of a protein?
A protein is a naturally occurring, extremely complex substance that consists of amino acid residues joined by peptide bonds. Proteins are present in all living organisms and include many essential biological compounds such as enzymes, hormones, and antibodies.
How can you define domain and motif is there any significance in bioinformatics or in proteomics?
These consensus sequence patterns are termed motifs and domains. A motif is a short conserved sequence pattern associated with distinct functions of a protein or DNA. The identification of motifs and domains in proteins is an important aspect of the classification of protein sequences and functional annotation.
What is a domain of a protein?
Protein Domains. A protein domain is any identifiable longer contiguous subsequence of a protein that can fold, function and exist independently of the rest of the protein chain or structure.
Do domain-domain interactions predict protein function and protein function?
Protein domains are independent evolutionary units, which define protein function. Multiple studies have demonstrated that domain-domain interactions (DDIs) are useful for predicting PPIs, since domains are directly involved in the intermolecular interactions (Memisevic et al., 2013; Shoemaker and Panchenko, 2007 ).
How do I identify conserved domains within a protein query sequence?
Use the CD-Search tool to identify conserved domains, or functional units, within a protein query sequence: Enter the protein query sequence, either as raw sequence data in FASTA format, or as a GI or Accession.
How do you determine the biological function of a protein?
Because most proteins in the cell function as part of a complex with other proteins, an important way to begin to characterize their biological roles is to identify their binding partners. If an uncharacterized protein binds to a protein whose role in the cell is understood, its function is likely to be related.