Sage-Tips

What causes sulfhemoglobinemia?

Sulfhemoglobinemia is caused by excessive exposure to sulphur-containing compounds, like medications that contain sulfonamides (such as sumatriptan or furosemide), nitrate fertilizer, or the overconsumption of nitrogenous vegetables like spinach (usually only in infants).

What is the meaning of sulfhemoglobinemia?

sulfhemoglobinemia, presence in the blood of sulfhemoglobin, the product of abnormal, irreversible binding of sulfur by the hemoglobin in the red blood cells, rendering them incapable of transporting oxygen. The condition may result from the chronic use of such drugs as acetanilide and phenacetin.

What is methemoglobinemia caused by?

Congenital methemoglobinemia is caused by a genetic defect that you inherit from your parents. This genetic defect leads to a deficiency of a certain enzyme, or protein. This protein is responsible for converting methemoglobin to hemoglobin.

How common is sulfhemoglobinemia?

Sulfhemoglobinemia is a rare condition that can result from exposure to any substance containing a sulfur atom with the ability to bind to hemoglobin. Cases of sulfhemoglobinemia have been reported from ingestions of phenacetin, dapsone, and sulfonamides.

Is Sulfhemoglobinemia real?

Sulfhemoglobinemia is a rare condition in which there is excess sulfhemoglobin (SulfHb) in the blood. The pigment is a greenish derivative of hemoglobin which cannot be converted back to normal, functional hemoglobin. It causes cyanosis even at low blood levels.

Can hemolysis be cured?

Hemolytic anemia may be curable if a doctor can identify the underlying cause and treat it.

Is Green blood bad?

For example, when our blood cells naturally die or get crushed, they produce bilirubin (yellow in color) and biliverdin (green) as they decompose. These are those lovely yellow and green marks around a bad bruise. Your liver cleans that out of your system as quickly as possible, because of its toxicity.

Who is at risk for methemoglobinemia?

Acquired methemoglobinemia is more frequent in premature infants and infants younger than 4 months, and the following factors may have a role in the higher incidence in this age group: Fetal hemoglobin may oxidize more easily than adult hemoglobin.

How does vitamin C treat methemoglobinemia?

Vitamin C is recommended for treatment of methemoglobinemia. It has been demonstrated that the reduction of the methemoglobin formation occurs at low vitamin C concentration in mice erythrocytes.

What race is most likely to get thalassemia?

Thalassemia is passed from parents to children through mutated hemoglobin genes. Certain ancestry. Thalassemia occurs most often in African Americans and in people of Mediterranean and Southeast Asian descent.

What color is real blood?

Human blood is red because hemoglobin, which is carried in the blood and functions to transport oxygen, is iron-rich and red in color. Octopuses and horseshoe crabs have blue blood. This is because the protein transporting oxygen in their blood, hemocyanin, is actually blue.

What color Bloods true?

red
Human blood is red because of the protein hemoglobin, which contains a red-colored compound called heme that’s crucial for carrying oxygen through your bloodstream.

What is sulfhemoglobinemia (SulfHb)?

Sulfhemoglobinemia (or sulfhaemoglobinaemia) is a rare condition in which there is excess sulfhemoglobin (SulfHb) in the blood. The pigment is a greenish derivative of hemoglobin which cannot be converted back to normal, functional hemoglobin.

What is hemoglobin sulfide bind syndrome?

It is a rare blood condition in which the β-pyrrole ring of the hemoglobin molecule has the ability to bind irreversibly to any substance containing a sulfur atom. When hydrogen sulfide (H 2 S) (or sulfide ions) and ferrous ions combine in the heme of hemoglobin, the blood is thus incapable of carrying oxygen .

How do you get methemoglobin and sulfhemoglobin together?

Methemoglobin and sulfhemoglobin may appear together in poisoning by phenacetin, acetanilid, or sulfanilamide. Dapsone (used to treat leprosy) and exposure to sulfurcontaining compounds either occupationally or from air pollution can also produce sulfhemoglobinemia.

What is the role of sulfhemoglobin in cyanosis?

Sulfhemoglobin can mimic the appearance of methemoglobinemia and should be considered when diagnosing those with cyanosis who have normal oxygen saturation and arterial blood gas readings. In this condition, a sulfur molecule, usually donated from glutathione, is incorporated into hemoglobin after the heme moiety is oxidized.