Table of Contents
Does IgA deficiency make you immunocompromised?
Although Selective IgA Deficiency is usually one of the milder forms of immunodeficiency, it may result in severe disease in some people.
Is IgA deficiency serious?
Most people with selective IgA deficiency are healthy, but some patients experience more frequent or severe infections. Patients with selective IgA deficiency have a slightly higher risk of having allergies (abnormal immune system reactions to environmental substances or food) and asthma (swollen airways in the lungs).
Is immune Deficiency autoimmune?
While not all individuals with immunodeficiency develop autoimmunity, nor are all individuals with autoimmunity immunodeficient, defects within certain components of the immune system carry a high risk for the development of autoimmune disease.
What autoimmune disease causes low IgA?
Autoimmune diseases, in which your immune system attacks particular organs or tissues in your own body, can be found with selective IgA deficiency. Common autoimmune conditions found with IgA deficiency include rheumatoid arthritis, lupus, celiac disease or inflammatory bowel disease.
Does IgA deficiency cause inflammation?
During infection, IgA-induced inflammation allows for a tailored immune response to counteract invading pathogens. However, when overactive or deficient, it may also lead to the development of chronic inflammation.
What does it mean to have a low IgA?
Having an IgA deficiency means that you have low levels of or no IgA in your blood. IgA is found in mucous membranes, mainly in the respiratory and digestive tracts. It is also found saliva, tears, and breastmilk. A deficiency seems to play a part in asthma and allergies.
How do you fix IgA deficiency?
There is no cure for IgA deficiency. Immunotherapy does not work to treat it. But you can take steps to lower your risk for illness or infection. These include taking antibiotics when you get sick.
What causes IgA deficiency?
Most cases of selective IgA deficiency are caused by inherited or sporadic mutations in specific genes. However, selective IgA deficiency can also be due to certain drugs.
What does low IgA deficiency mean?
Having an IgA deficiency means that you have low levels of or no IgA in your blood. IgA is found in mucous membranes, mainly in the respiratory and digestive tracts. It is also found saliva, tears, and breastmilk. A deficiency seems to play a part in asthma and allergies.
What does IgA deficiency stand for?
Selective immunoglobulin A (IgA) deficiency is a genetic immunodeficiency condition in which individuals do not make or have very low blood levels of IgA antibodies. IgA antibodies are responsible for fighting infections in mucus membranes throughout the body.