Sage-Tips

What age are people diagnosed with ankylosing spondylitis?

Age of disease onset usually peaks in the second and third decades of life. Approximately 80\% of patients with AS experience symptoms at ≤ 30 years of age, while only 5\% will present with symptoms at ≥ 45 years of age.

What is the main cause of ankylosing spondylitis?

Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called HLA-B27 are at a greatly increased risk of developing ankylosing spondylitis. However, only some people with the gene develop the condition.

Can you get ankylosing spondylitis in your 70s?

Ankylosing spondylitis and spondylarthropathies are generally observed in young patients but can be observed later in life or in persons >50 years of age.

Is ankylosing spondylitis hereditary?

Can ankylosing spondylitis be inherited? AS can run in families, and the HLA-B27 gene can be inherited from another family member. If you have AS and tests show you carry the HLA-B27 gene then there is a 1 in 2 chance that you could pass on the gene to any children you have.

Is ankylosing spondylitis hereditary disease?

Although ankylosing spondylitis can occur in more than one person in a family, it is not a purely genetic disease. Multiple genetic and environmental factors likely play a part in determining the risk of developing this disorder.

Does ankylosing spondylitis skip generations?

Is ankylosing spondylitis an autoimmune disease?

Ankylosing spondylitis affects men more often than women. The symptoms usually appear between the ages of 15 and 45 years. While there’s currently no cure for AS, there are many things you can do to help control your symptoms. Ankylosing spondylitis is an autoimmune disease.

Is ankylosing spondylitis (as) genetic?

Although ankylosing spondylitis (AS) can affect more than one person in a family, it is not a purely genetic disease. [1] While genes seem to play a role, the exact cause of AS is not known. It is considered to be multifactorial, which means that multiple genetic and environmental factors likely interact to affect a person’s risk to develop AS.

What are the signs and symptoms of ankylosing spondylitis?

Many people with ankylosing spondylitis have mild episodes of back pain and stiffness that come and go. But others have severe, ongoing back pain and stiffness. Other symptoms also may develop if other areas of the body are affected by the disease, such as:

What is the prognosis of ankylosing spondylitis?

Prognosis Prognosis. The long-term outlook for people with ankylosing spondylitis varies and is hard to predict. In many cases, at the onset of the disease, symptoms are not constant and are limited to one side of the body. As the disease progresses, pain and stiffness generally become more severe and more regular.

Can ankylosing spondylitis affect your eyes?

Ankylosing spondylitis affects men more often than women. Signs and symptoms typically begin in early adulthood. Inflammation also can occur in other parts of your body — most commonly, your eyes. There is no cure for ankylosing spondylitis, but treatments can lessen your symptoms and possibly slow progression of the disease.