Sage-Tips

Do statins help with stroke?

Studies show that statins can lower the risk of heart attack and stroke. Statins provide the most benefit for people at high risk of heart attack and stroke.

How effective are statins at preventing strokes?

A study of more than 135,000 people at risk for a heart attack or stroke found that those who took statins had a 25\% lower risk of having a heart attack or stroke compared to those who did not take statins. Statins are among the safest and most studied medications.

Why are statins given after a stroke?

Statins reduce the incidence of strokes among patients at increased risk for cardiovascular disease; whether they reduce the risk of stroke after a recent stroke or transient ischemic attack (TIA) remains to be established.

Which statin is best for stroke prevention?

The SPARCL trial provided the best evidence to support the role of atorvastatin for the secondary stroke prevention. Atorvastatin 80 mg/day reduced the incidence of recurrent ischemic stroke versus placebo (RRR: 16\%; P = 0.03) [73].

Does atorvastatin prevent stroke?

In the SPARCL (Stroke Prevention by Aggressive Reduction in Cholesterol Levels) trial, compared with placebo, the patients with a recent stroke or transient ischaemic attack without coronary heart disease randomised to atorvastatin 80 mg/day had a significant 16\% relative risk reduction of stroke and a 35\% reduction in …

Is taking statins worth the risk?

Research has shown that statins are highly effective in reducing the risk of fatal heart attack and stroke. But some people are reluctant to take these life-saving drugs. They worry about taking medicine every day for the rest of their life or have heard that statins have undesirable side effects.

Are statins contraindicated in hemorrhagic stroke?

In summary, mathematical decision analysis of the available data suggests that, because of the high risk of recurrent ICH in survivors of prior hemorrhagic stroke, even a small amplification of this risk by statins suffices to recommend that they should be avoided after ICH.

Can Atorvastatin cause a stroke?

Use of the statin drug Lipitor was associated with an increased risk of hemorrhagic stroke in the new analysis of a previously reported study. But using Lipitor was a less significant risk factor for hemorrhagic stroke than having had a previous brain bleed or having uncontrolled high blood pressure, researchers say.

Is rosuvastatin more effective than atorvastatin?

At the end of the titration-to-goal period, rosuvastatin was significantly more effective than atorvastatin on the primary efficacy measure, reducing LDL-C by 52\% compared with 46\% in the atorvastatin group (p < 0.0001) (table ​

When should I start taking statin after hemorrhagic stroke?

New initiation of statins within 3 days after ischemic stroke did not affect risk of subacute ICH within 6 months but might be associated with improved functional outcome and lower mortality.