Table of Contents
- 1 What are the next steps in genomic research?
- 2 What is the current status of gene therapy research?
- 3 What will be the future of gene therapy?
- 4 What are the recent or latest development in gene therapy?
- 5 What is the pattern of imprinting in the human genome?
- 6 How do scientists use genome editing to investigate diseases?
What are the next steps in genomic research?
What are the next steps in genomic research?
- Determine the function of genes and the elements that regulate genes throughout the genome.
- Find variations in the DNA sequence among people and determine their significance.
- Discover the 3-dimensional structures of proteins and identify their functions.
What is the current status of gene therapy research?
So, there is no clinical trial on human germline gene therapy. Currently, somatic gene therapy is safe for the management of several disorders in human beings. Gene therapy effectively treats several diseases due to increased understanding of disease pathogenesis and improved gene delivery technologies.
What are the ethical issues of the Human Genome Project?
The original issues identified in the ELSI program announcement were: questions of fairness in the use of genetic information; the impact of genetic information on individuals; privacy and confidentiality of genetic information; the impact of the HGP on genetic counseling; the impact of genetic information on …
What are 3 of the next steps in studying the human genome?
Generating a draft sequence of the human genome involved three steps: selecting the BAC clones to be sequenced, sequencing them and assembling the individual sequenced clones into an overall draft genome sequence.
What will be the future of gene therapy?
Because of its accuracy, gene therapy has the potential to eliminate cancer cells without damaging normal, healthy tissue. Furthermore, cancer gene therapies may provide alternatives when a disease does not respond to other older treatments.
What are the recent or latest development in gene therapy?
Results: A large variety of therapeutic genes are under investigation, such as tumour suppressor, suicide, antiangiogenesis, inflammatory cytokine and micro-RNA genes. Recent progress concerns new vectors, such as oncolytic viruses, and the synergy between viral gene therapy, chemotherapy and radiation therapy.
What is the Human Genome Project and why is it important?
The idea of the Human Genome Project was born in the 1970s, when scientists learned how to ‘clone’ small bits of DNA, around the size of a gene. To clone DNA, scientists cut out a fragment of human DNA from the long strand and then incorporate it into the genome of a bacteria, or a bacterial virus.
What is the blueprint of a living organism?
The blueprint for any living organism is contained in its DNA. DNA is a long molecule made up of many smaller units, called nucleotide bases. The order, or sequence, of the bases within the DNA provides the instructions for creating that organism—the genetic code.
What is the pattern of imprinting in the human genome?
The human genome contains two copies of every gene-one copy inherited from the mother and one from the father. For a small number of genes, only the copy from the mother gets switched on; for others, only the copy from the father is turned on. This pattern is called imprinting.
How do scientists use genome editing to investigate diseases?
One way that scientists use genome editing is to investigate different diseases that affect humans. They edit the genomes of animals, like mice and zebrafish, because animals have many of the same genes as humans. For example, mice and humans share about 85 percent of their genes!