Table of Contents
What is Delta hepatitis?
Hepatitis D, also known as “delta hepatitis,” is a liver infection caused by the hepatitis D virus (HDV). Hepatitis D only occurs in people who are also infected with the hepatitis B virus.
What does Delta agent mean?
The delta agent seems to be a defective RNA virus which is dependent on a helper function provided by hepatitis B-virus. Delta agent infection occurs by parenteral transmission either together with hepatitis B-virus, or superimposed on chronic HBV infection.
HDV superinfection accelerates the progression of chronic HBV in 70\%–90\% of people, regardless of age (2). Although HDV suppresses the replication of HBV, cirrhosis occurs up to a decade earlier in HDV-superinfected persons compared with those infected with HBV alone (2).
What is the difference between hepatitis B and D?
Hepatitis B is a life-threatening liver infection that is caused by the hepatitis B virus, whereas, hepatitis D infection only occurs in people who are infected with the hepatitis B virus. It replicates autonomously within hepatocytes, but requires hepatitis B surface antigen for proliferation.
What are D causes of hepatitis?
Hepatitis D is caused by HDV. The infection is contagious and spread through direct contact with the bodily fluids of an infected person. It can be transmitted through: urine.
What is chronic viral hepatitis B with delta agent?
Delta agent. Hepatitis D is a viral infection caused by the hepatitis D virus (previously called the Delta agent). It causes symptoms only in people who also have hepatitis B infection. Hepatitis B is also known as serum hepatitis and is spread through blood and sexual contact.
What type of virus is hepatitis D?
Hepatitis D is a type of viral hepatitis caused by the hepatitis delta virus (HDV).
What is anti hepatitis D virus?
Clinical Information Acute HBV-HDV coinfection usually follows a self-limited clinical course with spontaneous resolution but may have a fulminant clinical presentation.
Where is Hepatitis D endemic?
It is endemic in the developing world, with a high prevalence in South America. HDV infection is limited to patients who have HBV infection and, like hepatitis B, is acquired parenterally. Worldwide, about 5\% of HBV carriers are anti-HDV-positive. Delta hepatitis remains a common problem among intravenous drug users.
Why does hepatitis D need hepatitis B?
Hepatitis D virus (HDV) is a defective RNA virus which requires the help of hepatitis B virus (HBV) virus for its replication and assembly of new virions. HDV genome contains only one actively transcribed open reading frame which encodes for two isoforms of hepatitis delta antigen.
What is true about hepatitis D?
Hepatitis D, also known as the hepatitis delta virus, is an infection that causes the liver to become inflamed. This swelling can impair liver function and cause long-term liver problems, including liver scarring and cancer. The condition is caused by the hepatitis D virus (HDV).
How does hepatitis D replicate?
Unlike most RNA viruses, HDV does not encode its own replicase or RNA-dependant RNA polymerase to replicate its genome. Rather, it makes use of cellular RNA polymerases which are DNA-dependant RNA polymerases.
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