What are the three first line drugs for the treatment of chronic hepatitis B?

What are the three first line drugs for the treatment of chronic hepatitis B?

Currently, pegylated interferon alfa (PEG-IFN-a), entecavir (ETV), and tenofovir disoproxil fumarate (TDF) are the first-line agents in the treatment of hepatitis B disease.

Is interferon used to treat chronic hepatitis B?

Interferon is a powerful drug used to treat hepatitis types B, C, and D. It can prevent serious liver damage, but it also has many side effects, some of them serious. Interferon is the drug of choice for treating several chronic forms of viral hepatitis, including hepatitis B and C.

What is the new treatment for hepatitis B?

VIR-2218 is an investigational GalNAc-conjugated small interfering ribonucleic acid (siRNA) therapeutic in development for functional cure of chronic hepatitis B virus infection (CHB). VIR-2218 was created using Enhanced Stabilization Chemistry Plus, which retains in vivo potency while reducing off-target effects.

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Which drug is most effective against the hepatitis B virus?

Tenofovir is effective at reducing the amount of hepatitis B virus in the body. Some studies show that entecavir works better than lamivudine or adefovir. Tenofovir works better than adefovir against hepatitis B virus that is resistant to lamivudine.

How long is chronic hepatitis B treatment?

Duration of treatment is at least 1 year with lamivudine and adefovir; longer duration of treatment is needed in most patients, but the optimal duration of treatment and the criteria for stopping treatment have not been established.

What are interferon treatments?

Interferon alfa-2b injection is used to treat hepatitis B and C, lymphoma (lymph node cancer), malignant melanoma (skin cancer), genital warts, hairy cell leukemia (blood cell cancer), and Kaposi sarcoma (AIDS-related tumor). Interferons are substances produced by cells in the body to help fight infections and tumors.

What is the difference between interferon and peginterferon?

Overview. Pegylated interferon, usually called peginterferon, is a chemically modified form of the standard interferon that treats hepatitis C and rarely hepatitis B. The difference between interferon and peginterferon is the PEG, which stands for a molecule called polyethylene glycol.

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What is acute and chronic hepatitis B?

When a person is first infected with the hepatitis B virus, it is called an “acute infection” (or a new infection). Many people are able to naturally get rid of an acute infection. If the infection persists for more than 6 months, it is considered a “chronic infection.”

What is Lamivudine used for?

Lamivudine (Epivir-HBV) is used to treat hepatitis B infection. Lamivudine is in a class of medications called nucleoside reverse transcriptase inhibitors (NRTIs). It works by decreasing the amount of HIV and hepatitis B in the blood.